Senior Technician Bioanalytical Development

Senior Technician Bioanalytical Development

to work in our Leiden office. Leyden Labs is a fast-growing biotech company and currently expanding the Bioanalytical Development team. You will work on the development and qualification of assays for usage in pharmacokinetic (PK) studies, for the identification of anti-drug antibodies (ADA) in preclinical in vivo animal studies and for support of CMC characterization and development studies.

Under supervision of the Scientist (Pre) Clinical Assay Development, you will develop and qualify a variety of state-of-the-art ligand-binding assays employing both ELISA and additional high-throughput platforms (MSD, SPR).

In your role as Senior Technician Bioanalytical Development, you will be responsible for planning, performing and reporting assay runs to support the assay development team and subsequently (pre)clinical studies. You have a profound understanding of assay development for large molecules, and you will be working in a small team of technicians and scientists. The team closely collaborates with internal and external development and research teams.

More about the team:
Bioanalytical Development is part of the Preclinical Development and CMC department. Next to Bio-analytical development, the department consists of two other sub-departments: CMC and Protein Chemistry. You will be joining our Associate Director (Pre) Clinical Assay Development, Menno van Lummel. Bioanalytical Development plays a crucial role in the development and validation of assays required for drug assessment and subsequently paving the way to human clinical trials.

Why would you want to work with us:
Leyden Labs is a growing company with great ambitions, where you can play a supporting role, so that the development of our products can be carried out. In 2021, The company successfully completed Series A and B funding rounds, worth of almost €200MIO. This illustrates trust in the company’s strategy. We are driven professionals that help and encourage each other to deliver their best and achieve the highest standards. We strive for a fantastic life for all, including our team members.

This will be on your plate for the next 3 to 6 months:

• Experiments for method development and qualification and data analysis
• Write SOP’s and work instructions
• Participate and execute general laboratory tasks and improve laboratory procedures
• Prepare reagents
• Report data in (electronic) laboratory notebooks (eLN), assay forms and overview sheets
• Communicate method and sample issues to the team
• Perform troubleshooting in case of aberrant test results
• Maintain method trending files

What we offer:

• A challenging fulltime position (32-40 hours/week) in a dynamic scale-up bio-pharmaceutical company
• You will contribute to the development of next generation medicines providing protection against all known airborne viruses
• You will join a stimulating working environment and become part of a driven team
• We offer attention and possibilities for personal and professional growth

• Educational background BSc education specialized in e.g. Biomedical, Biotechnology, Life Sciences 
• A minimum of 5 years of experience within biotech and in particular assay development 
• Mandatory knowledge of ligand-binding assays (ELISA, ECLIA (MSD)) and cell culturing 
• Knowledge of assay qualification/validation design of experiment (DoE) principle and international guidelines (ICH, EMA, FDA) is an advantage 
• Preferably experience with ligand-binding assays employing high-throughput platforms, e.g. Surface Plasmon Resonance (SPR). 
• Good written and oral communication skills in both Dutch and English 
• A highly structured way of working and meticulous lab notebook keeping 
• Experience with electronic lab journals (eLN) is an advantage 
• Knowledge of virology and immunology is an advantage 

More about you: